Willow Rosenberg and Xander Harris - Buffy the Vampire Slayer
Previous vampire slayers might have preferred to go it alone but Buffy surrounds herself with a tight demon-fighting crew, affectionately known as the Scooby Gang. Her best friends, Willow and Xander, used to date when they were five years old (but broke up over a stolen Barbie), but have now turned their attention to keeping Buffy out of trouble (or, at least, joining her when she gets into trouble).
Alexander "Lex" Luthor - Smallville
Long before he was his arch nemesis, Lex Luthor was actually Clark Kent's best friend. Haven't most of us had friendships like that? Lex is the son of a billionaire businessman who loves money more than he does his own son. Maybe that's why Lex descends into evil throughout the Smallville series.
Lilly Truscott - Hannah Montana
Also known as Lola Lufnagle, Lilly is Miley Stewart's BFF and confidant. This skatboarding, boy-crazy chica may be quick-tempered but she's always got her best friend's back - both when she is a rock star and just a regular girl. We could all use a friend like this fun-loving girl.
Screech Powers - Saved by the Bell
This awkward, nerdy kid has been tagging along with Zack Morris since he was just a tyke. He's loyal, eccentric and a little delusional (he thinks he's quite a ladie's man). Screech may have been a nerd but he was totally comfortable with his geekiness and always up for a laugh - even if it was at his expense.
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